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Lambda-IgLC antibody (FITC)

The Mouse Monoclonal anti-Lambda-IgLC antibody has been validated for FACS. It is suitable to detect Lambda-IgLC in samples from Human.
Catalog No. ABIN7076305

Quick Overview for Lambda-IgLC antibody (FITC) (ABIN7076305)

Target

Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

Reactivity

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Human

Host

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Mouse

Clonality

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Monoclonal

Conjugate

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This Lambda-IgLC antibody is conjugated to FITC

Application

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Flow Cytometry (FACS)

Grade

GMP Grade (Analyte)

Clone

HP6054
  • Purpose

    Anti-Lambda Light Chain FITC Antibody

    Characteristics

    The clone HP6054 specifically binds with both soluble and membrane bound human lambda light chain of immunoglobulin but not binds with the kappa light chain or heavy chain. Lambda light chains are primarily expressed on the surface of B cells in lymphoid tissues. Each B cell expresses only one class of light chain kappa or lambda. In serum of a healthy individual, the total kappa to lambda ratio is approximately 3:1 while measuring as intact whole antibodies or 1:1.5 while measuring as free light chains. Various clinical research data claim that any highly divergent ratio of kappa to lambda indicative of neoplasm. HP6054 is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas.

    Purification

    Purified

    Purity

    >95 %

    Immunogen

    Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads

    Isotype

    IgG2a, kappa
  • Application Notes

    FC: 5 µL/test We recommend that every lab carries out an initial titration study before running your samples to ensure that the optimal concentration is selected for your application.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS, pH 7.2, 0.09 % Sodium azide and 0.2 % (w/v) BSA

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    2-8°C, Conjugated antibodies should never be frozen.
  • Target

    Lambda-IgLC (lambda Light Chain (Lambda-IgLC))

    Alternative Name

    Ig Lambda Light Chain

    Gene ID

    3535
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