IL7R antibody (PE)

Catalog No. ABIN7076849

The PE-conjugated Mouse Monoclonal anti-IL7R antibody (Clone 4G8) (ABIN7076849) specifically detects IL7R in FACS. The antibody is reactive with Human samples.

Quick Overview for IL7R antibody (PE) (ABIN7076849)

Target: IL7R (Interleukin 7 Receptor (IL7R))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL7R antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Grade: GMP Grade

Clone: 4G8

Product Details anti-IL7R Antibody (PE)

Purpose: CD127 PE Antibody

Characteristics: The clone 4G8, a mouse monoclonal antibody selectively recognizes a 60-90 kDa surface type 1 transmembrane glycoprotein antigen known as CD127 or IL-7 receptor α chain (IL-7Rα). CD127 forms a heterodimer with the common γ chain of the receptors of several cytokines such as IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. It is widely expressed on different subsets of B cells, peripheral T cells and bone marrow stromal cells. CD127 plays important role in the generation of memory and effector T cells as well as functional B cells.

Purification: Purified

Purity: >95 %

Immunogen: Purified homodimeric form of T-ALL mutant and monomeric WT hIL-7Ralpha conjugated KLH

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C, Conjugated antibodies should never be frozen.

Target Details for IL7R

Target: IL7R (Interleukin 7 Receptor (IL7R))

Alternative Name: CD127

Gene ID: 3575

UniProt: P16871

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size