VLDLR antibody (AA 551-650)

Catalog No. ABIN705551

There is 1 publication for this product available. The Rabbit Polyclonal anti-VLDLR antibody is suitable to detect VLDLR in samples from Human. It has been validated for WB and FACS.

Quick Overview for VLDLR antibody (AA 551-650) (ABIN705551)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VLDLR antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Product Details anti-VLDLR Antibody

Binding Specificity: AA 551-650

Purpose: VLDL Receptor Polyclonal Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VLDL Receptor

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-VLDLR antibody (ABIN705551)

Fredriksson, Mishra, Lam, Mushaben, Cuento, Meyer, Yao, Keeran, Nugent, Qu, Yu, Yang, Raghavachari, Dagur, McCoy, Levine: "The very low density lipoprotein receptor attenuates house dust mite-induced airway inflammation by suppressing dendritic cell-mediated adaptive immune responses." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 10, pp. 4497-509, (2014) (PubMed).

Target Details for VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Alternative Name: VLDL Receptor

Background:

Synonyms: CARMQ1, CHRMQ1, VLDLRCH, Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Background: Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity).

Gene ID: 7436

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin