ATP1A1 antibody (PE-Cy5)

Catalog No. ABIN705968

The Rabbit Polyclonal anti-ATP1A1 antibody has been validated for WB. It is suitable to detect ATP1A1 in samples from Human, Rat, Mouse, Pig, Chicken and Guinea Pig.

Quick Overview for ATP1A1 antibody (PE-Cy5) (ABIN705968)

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Reactivity: Human, Rat, Mouse, Pig, Chicken, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP1A1 antibody is conjugated to PE-Cy5

Application: Western Blotting (WB)

Product Details anti-ATP1A1 Antibody (PE-Cy5)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Pig,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ATP1A1

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ATP1A1

Target: ATP1A1 (Sodium Potassium ATPase, alpha1 (ATP1A1))

Alternative Name: ATP1A1

Background:

Synonyms: Na,K-ATPase alpha-1, Na+/K+ ATPase 1, beta Sodium Potassium ATPase, Sodium pump 1, ATP1A4, ATP1AL2, ATP1B, ATP1B1, ATPase Na+/K+ transporting alpha 1 polypeptide, ATPase Na+/K+ transporting alpha 4 polypeptide, ATPase Na+/K+ transporting beta 1 polypeptide, MGC1798, MGC25056, MGC3285, MGC51750, Sodium/potassium dependent ATPase beta 1 subunit, Sodium/potassium transporting ATPase alpha 1 chain, Sodium/potassium transporting ATPase subunit beta 1, Sodium Potassium ATPase, alpha 1 Sodium Potassium ATPase.

Background: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+-ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 1 subunit. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May2009].

Molecular Weight: 113kDa

Gene ID: 476

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Proton Transport, Ribonucleoside Biosynthetic Process