Recombinant alpha 2 Macroglobulin antibody

Catalog No. ABIN7090747

The Mouse Monoclonal anti-alpha 2 Macroglobulin antibody is suitable to detect alpha 2 Macroglobulin in samples from Human. It has been validated for WB.

Quick Overview for Recombinant alpha 2 Macroglobulin antibody (ABIN7090747)

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This alpha 2 Macroglobulin antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-alpha 2 Macroglobulin Antibody

Purpose: Alpha 2 Macroglobulin Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human Alpha 2 Macroglobulin

Isotype: IgG2a, kappa

Application Details

Application Notes: WB(1:300-5000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for alpha 2 Macroglobulin

Target: alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))

Alternative Name: Alpha 2 Macroglobulin

Background:

Synonyms: a2-Macroglobulin, A2M, _-2M, A2MG_HUMAN, Alpha 2 M, Alpha 2M, Alpha-2-M, Alpha-2-macroglobulin, Alpha-2 Macroglobulin, Alpha 2-Macroglobulin, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, CPAMD5, DKFZp779B086, FWP007, S863 7.

Background: Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq, Jul 2008].

Gene ID: 2

UniProt: P01023

Pathways: Lipid Metabolism