Aurora Kinase B antibody

Catalog No. ABIN7090774

The Rabbit Monoclonal anti-Aurora Kinase B antibody has been validated for WB, IF, IHC (p) and ICC. It is suitable to detect Aurora Kinase B in samples from Human.

Quick Overview for Aurora Kinase B antibody (ABIN7090774)

Target: Aurora Kinase B (AURKB)

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Aurora Kinase B antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: G6D12

Product Details anti-Aurora Kinase B Antibody

Cross-Reactivity: Human

Predicted Reactivity: Mouse

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human Aurora B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for Aurora Kinase B

Target: Aurora Kinase B (AURKB)

Alternative Name: Aurora B

Background:

Synonyms: STK-1, serine/threonine kinase 12, aurora-B, aurora-1, aurora kinase B-Sv1, aurora kinase B-Sv2, ARK-2, STK-1, STK1, aurora-related kinase 2, aurora/IPL1-related kinase 2, serine/threonine-protein kinase aurora-B, aurora- and Ipl1-like midbody-associated protein 1, AURKB, AIK2, AIM-1, AIM1, ARK2, AurB, aurkb-sv1, aurkb-sv2, IPL1, STK12, STK5, AIRK2, AURKB_HUMAN.

Background: This gene encodes a member of the aurora kinase subfamily of serine/threonine kinases. The genes encoding the other two members of this subfamily are located on chromsomes 19 and 20. These kinases participate in the regulation of segregation of chromosomes during mitosis and meiosis through association with microtubules. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

Gene ID: 9212

UniProt: Q96GD4

Pathways: TCR Signaling, Cell Division Cycle, Maintenance of Protein Location, Hepatitis C, Toll-Like Receptors Cascades