CD19 antibody (AbBy Fluor® 488)

Catalog No. ABIN7090841

The AbBy Fluor® 488-conjugated Mouse Monoclonal anti-CD19 antibody (Clone HI19a) (ABIN7090841) specifically detects CD19 in FACS. The antibody is reactive with Human samples.

Quick Overview for CD19 antibody (AbBy Fluor® 488) (ABIN7090841)

Target: CD19 (CD19 Molecule (CD19))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD19 antibody is conjugated to AbBy Fluor® 488

Application: Flow Cytometry (FACS)

Clone: HI19a

Product Details anti-CD19 Antibody (AbBy Fluor® 488)

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CD19

Isotype: IgG1

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for CD19

Target: CD19 (CD19 Molecule (CD19))

Alternative Name: CD19

Background:

Synonyms: Antibody deficiency due to defect in CD19, included, AW495831, B lymphocyte antigen CD19, B lymphocyte surface antigen B4, B4, CD 19, CD19 antigen, CD19 Molecule, Cd19 protein, Differentiation Antigen CD19, Leu 12, Leu12, Lymphocyte Surface Antigen, MGC109570, MGC12802, T-cell surface antigen Leu-12, CD19_HUMAN.

Background: CD19 is a transmembrane glycoprotein that is delectively expressed on the cell surface of B-lymphocytes,where it activates intracellular signaling cascades involving both Ras and phosphatidylinositol 3-kinase pathways.Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.

Gene ID: 930

UniProt: P15391

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway