CYP27B1 antibody (AA 411-510)

Catalog No. ABIN7091022

This Mouse Monoclonal antibody specifically detects CYP27B1 in WB. It exhibits reactivity toward Human.

Quick Overview for CYP27B1 antibody (AA 411-510) (ABIN7091022)

Target: CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CYP27B1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: G4E2

Product Details anti-CYP27B1 Antibody

Binding Specificity: AA 411-510

Purpose: CYP27B1 Monoclonal Antibody

Cross-Reactivity: Human

Purification: Purified by Protein G.

Immunogen: KLH conjugated synthetic peptide derived from human CYP27B1

Isotype: IgG1

Application Details

Application Notes: WB(WB=1:500-1000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CYP27B1

Target: CYP27B1 (Cytochrome P450, Family 27, Subfamily B, Polypeptide 1 (CYP27B1))

Alternative Name: CYP27B1

Background:

Synonyms: 1alpha(OH)ase, 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, 25-hydroxyvitamin D-1 alpha hydroxylase, 25-OHD-1 alpha-hydroxylase, Calcidiol 1-monooxygenase, CP27B_HUMAN, CP2B, CYP1, CYP1ALPHA, CYP27B, Cytochrome p450 27B1, Cytochrome p450 27B13, Cytochrome P450 family 27 subfamily B polypeptide 1, Cytochrome P450 subfamily XXVIIB (25-hydroxyvitamin D-1-alpha-hydroxylase) polypeptide 1, Cytochrome P450 subfamily XXVIIB polypeptide 1, Cytochrome P450C1 alpha, Cytochrome P450VD1-alpha, mitochondrial, P450C1 alpha, P450c1, P450C1-alpha, P450VD1-alpha, PDDR, VD3 1A hydroxylase, VDD1, VDDR, VDDR I, VDDRI, VDR.

Background: Catalyzes the conversion of 25-hydroxyvitamin D3 (25(OH)D) to 1-alpha,25-dihydroxyvitamin D3 (1,25(OH)2D) plays an important role in normal bone growth, calcium metabolism, and tissue differentiation.

Gene ID: 1594

UniProt: O15528

Pathways: Metabolism of Steroid Hormones and Vitamin D