EIF2S1 antibody

Catalog No. ABIN7091087

The Mouse Monoclonal anti-EIF2S1 antibody (Clone B5Y8) (ABIN7091087) specifically detects EIF2S1 in WB. The antibody is reactive with Human samples.

Quick Overview for EIF2S1 antibody (ABIN7091087)

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EIF2S1 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: B5Y8

Product Details anti-EIF2S1 Antibody

Predicted Reactivity: Human,Mouse,Rat

Immunogen: Recombinant human EIF2A.

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EIF2S1

Target: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Alternative Name: EIF2S1

Background:

Synonyms: EIF2A, CDA 02, CDA02, eIF 2 alpha, EIF 2, EIF 2A, EIF-2alpha, EIF2, EIF2alpha, eIF2S1, Eukaryotic Translation Initiation Factor 2 alpha, Eukaryotic translation initiation factor 2 subunit 1 alpha 35 kDa, Eukaryotic translation initiation factor 2 subunit alpha, IF2A_HUMAN.

Background: Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

Gene ID: 1965

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C