FKBP1A antibody

Catalog No. ABIN7091114

This anti-FKBP1A antibody is a Mouse Monoclonal antibody detecting FKBP1A in WB. Suitable for Human.

Quick Overview for FKBP1A antibody (ABIN7091114)

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This FKBP1A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: D3J6

Product Details anti-FKBP1A Antibody

Predicted Reactivity: Human,Mouse,Rat

Immunogen: KLH conjugated synthetic peptide derived from human FKBP1A

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FKBP1A

Target: FKBP1A (FK506 Binding Protein 1A, 12kDa (FKBP1A))

Alternative Name: FKBP1A

Background:

Synonyms: FKBP12, FKB1A_HUMAN, 12 kDa FK506-binding protein, 12 kDa FKBP, FK506 binding protein 1, FK506 binding protein 12, FK506 binding protein 1A 12 kDa, FK506 binding protein 1A, FK506 binding protein T cell 12 kD, FK506-binding protein 1A, FKBP 12, FKBP 1A, FKBP-12, FKBP-1A, FKBP1, FKBP12 Exip3, FKBP12C, Immunophilin FKBP12, Peptidyl prolyl cis trans isomerase, Peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase FKBP1A, PKC12, PKCI2, PPIase, PPIase FKBP1A, Protein kinase C inhibitor 2, Rotamase.

Background: May play a role in modulation of ryanodine receptor isoform-1 (RYR-1), a component of the calcium release channel of skeletal muscle sarcoplasmic reticulum. There are four molecules of FKBP12 per skeletal muscle RYR. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.

Gene ID: 2280

UniProt: P62942

Pathways: Negative Regulation of Transporter Activity, Methionine Biosynthetic Process