Growth Hormone Receptor antibody (AA 551-638) (HRP)

Catalog No. ABIN7091182

The Rabbit Polyclonal anti-Growth Hormone Receptor antibody is suitable to detect Growth Hormone Receptor in samples from Human. It has been validated for WB and ELISA.

Quick Overview for Growth Hormone Receptor antibody (AA 551-638) (HRP) (ABIN7091182)

Target: Growth Hormone Receptor (GHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Growth Hormone Receptor antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA

Product Details anti-Growth Hormone Receptor Antibody (HRP)

Binding Specificity: AA 551-638

Cross-Reactivity: Human

Predicted Reactivity: Dog,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GHR

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Target Details for Growth Hormone Receptor

Target: Growth Hormone Receptor (GHR)

Alternative Name: Growth hormone receptor

Background:

Synonyms: GH receptor, GHBP, GHR, Growth hormone receptor precursor, Serum binding protein, Somatotropin receptor, GHR_HUMAN.

Background: Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to the JAK2/STAT5 pathway.
The soluble form (GHBP) acts as a reservoir of growth hormone in plasma and may be a modulator/inhibitor of GH signaling.
Isoform 2 up-regulates the production of GHBP and acts as a negative inhibitor of GH signaling.

Gene ID: 2690

UniProt: P10912

Pathways: NF-kappaB Signaling, JAK-STAT Signaling, Response to Growth Hormone Stimulus