Recombinant HBA1 antibody

Catalog No. ABIN7091200

The Rabbit Monoclonal anti-HBA1 antibody is suitable to detect HBA1 in samples from Human. It has been validated for IHC (p), IF (p) and IHC (fro).

Quick Overview for Recombinant HBA1 antibody (ABIN7091200)

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HBA1 antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-HBA1 Antibody

Purpose: HBA1 Recombinant Antibody

Cross-Reactivity: Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HBA1

Isotype: IgG

Application Details

Application Notes: IHC-P(IHC-P(1:50-200)), IHC-F(IHC-F(1:50-200)), IF(IHC-P)(IF(IHC-P)(1:50-200))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for HBA1

Target: HBA1 (Hemoglobin, alpha 1 (HBA1))

Alternative Name: HBA1

Background:

Synonyms: Alpha 1 globin, Alpha globin, Alpha one globin, Alpha-globin, HBA_HUMAN, HBA2, Hemoglobin alpha 1, Hemoglobin alpha 1 chain, Hemoglobin alpha 1 globin chain, Hemoglobin alpha 2, Hemoglobin alpha chain, Hemoglobin subunit alpha, MGC126895, MGC12689.

Background: he human alpha globin gene cluster located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97 % of the total hemoglobin, alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3 % of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1, some nondeletion alpha thalassemias have also been reported. [provided by RefSeq, Jul 2008]

Gene ID: 3039

UniProt: P69905