URI1 antibody

Catalog No. ABIN7091805

This Rabbit Monoclonal antibody specifically detects URI1 in WB, IF, IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for URI1 antibody (ABIN7091805)

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This URI1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: U3F5

Product Details anti-URI1 Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STMN1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF()
ICC 1:100-500

Restrictions: For Research Use only

Handling

Concentration: 1 mg/mL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for URI1

Target: URI1 (URI1, Prefoldin-Like Chaperone (URI1))

Alternative Name: URI1

Background:

Synonyms: C19orf2, Chromosome 19 open reading frame 2, NNX3, PPP1R19, Protein NNX3, Protein phosphatase 1 regulatory subunit 19, RMP_HUMAN, RNA polymerase II subunit 5 mediating protein, RNA polymerase II subunit 5-mediating protein, RPB5 mediating protein, RPB5-mediating protein, Unconventional prefoldin RPB5 interactor 1, Unconventional prefoldin RPB5 interactor, URI, URI1, prefoldin-like chaperone.

Background: This gene encodes member of the prefoldin family of molecular chaperones. The encoded protein functions as a scaffolding protein and plays roles in ubiquitination and transcription, in part though interactions with the RNA polymerase II subunit RPB5. This gene may play a role in multiple malignancies including ovarian cancer and hepatocellular carcinoma. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 22. [provided by RefSeq, Nov 2011]

Gene ID: 8725

UniProt: O94763