TPX2 antibody (AA 551-650) (Biotin)

Catalog No. ABIN706408

This Rabbit Polyclonal antibody specifically detects TPX2 in WB, ELISA, IHC (p) and IHC (fro). It exhibits reactivity toward Mouse.

Quick Overview for TPX2 antibody (AA 551-650) (Biotin) (ABIN706408)

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TPX2 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-TPX2 Antibody (Biotin)

Binding Specificity: AA 551-650

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TPX2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for TPX2

Target: TPX2 (TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (TPX2))

Alternative Name: TPX2

Background:

Synonyms: C20ORF1, C20orf2, Chromosome 20 Open Reading Frame 1, Dferentially expressed in cancerous and non-cancerous lung cells 2, Dferentially expressed in cancerous and noncancerous lung cells 2, Dferentially expressed in lung cells 2, Dferentially expressed in lung cells, DIL 2, DIL-2, DIL2, FLS353, GD:C20orf1, HCA 519, HCA519, HCTP 4, HCTP4, Hepatocellular carcinoma associated antigen 519, Hepatocellular carcinoma-associated antigen 519, p100, Preferentially expressed in colorectal cancer, Protein FLS353, REPP 86, repp86, Restricted expression proliferation associated protein 100, Restricted expression proliferation-associated protein 100, Targeting protein for XKLP2, TPX 2, TPX2, TPX2 microtubule associated homolog, TPX2 microtubule associated protein homolog, TPX2_HUMAN.

Background: TPX2 is essential for spindle pole and mitotic spindle formulation, playing a role in the S and G2 phases of mitosis. It is also critical for the function of protein kinase Aurora A. TPX2 autophosphorylates Aurora A, targeting it to the spindle apparatus and allowing it to function in eukaryotic meiotic and mitotic cell cycles. TPX2 has also been found to be highly expressed in cancer cells.

Gene ID: 22974