MACC1 antibody (AA 761-852) (HRP)

Catalog No. ABIN706535

The Rabbit Polyclonal anti-MACC1 antibody is suitable to detect MACC1 in samples from Human and Rat. It has been validated for WB, ELISA, IHC (p) and IHC (fro).

Quick Overview for MACC1 antibody (AA 761-852) (HRP) (ABIN706535)

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MACC1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-MACC1 Antibody (HRP)

Binding Specificity: AA 761-852

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MACC1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MACC1

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Alternative Name: MACC1

Background:

Synonyms: 7A5, SH3BP4L, Metastasis-associated in colon cancer protein 1, SH3 domain-containing protein 7a5, MACC1

Background: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo.

Gene ID: 346389

UniProt: Q6ZN28