OXCT1 antibody

Catalog No. ABIN7111113

This anti-OXCT1 antibody is a Rabbit Polyclonal antibody detecting OXCT1 in WB, ELISA, IHC and IF. Suitable for Human, Mouse and Rat.

Quick Overview for OXCT1 antibody (ABIN7111113)

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXCT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-OXCT1 Antibody

Purpose: OXCT1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: 3-oxoacid CoA transferase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for OXCT1

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Alternative Name: OXCT1

Background:

Synonyms: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT)|3-oxoacid CoA-transferase 1|Somatic-type succinyl-CoA:3-oxoacid CoA-transferase (SCOT-s)|Succinyl-CoA:3-oxoacid CoA transferase|OXCT1|OXCT|SCOT

Background: This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

Molecular Weight: 56 kDa

Gene ID: 5019

UniProt: P55809

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis