OXCT1 antibody

Catalog No. ABIN7111114

This Rabbit Polyclonal antibody specifically detects OXCT1 in WB, ELISA, IHC, IP and IF. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for OXCT1 antibody (ABIN7111114)

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OXCT1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-OXCT1 Antibody

Purpose: OXCT1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: 3-oxoacid CoA transferase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:1000-1:4000, IP: 1:500-1:2000, IHC: 1:50-1:500, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for OXCT1

Target: OXCT1 (3-Oxoacid CoA Transferase 1 (OXCT1))

Alternative Name: OXCT1

Background:

Synonyms: Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial (SCOT)|3-oxoacid CoA-transferase 1|Somatic-type succinyl-CoA:3-oxoacid CoA-transferase (SCOT-s)|Succinyl-CoA:3-oxoacid CoA transferase|OXCT1|OXCT|SCOT

Background: This gene encodes a member of the 3-oxoacid CoA-transferase gene family. The encoded protein is a homodimeric mitochondrial matrix enzyme that plays a central role in extrahepatic ketone body catabolism by catalyzing the reversible transfer of coenzyme A from succinyl-CoA to acetoacetate. Mutations in this gene are associated with succinyl CoA:3-oxoacid CoA transferase deficiency.

Molecular Weight: 56 kDa

Gene ID: 5019

UniProt: P55809

Pathways: Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis