PAPSS2 antibody

Catalog No. ABIN7111122

This anti-PAPSS2 antibody is a Rabbit Polyclonal antibody detecting PAPSS2 in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for PAPSS2 antibody (ABIN7111122)

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPSS2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-PAPSS2 Antibody

Purpose: PAPSS2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: 3'-phosphoadenosine 5'-phosphosulfate synthase 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for PAPSS2

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Alternative Name: PAPSS2

Background:

Synonyms: Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPS synthase 2, PAPSS 2)|Sulfurylase kinase 2 (SK 2, SK2)|PAPSS2|ATPSK2

Background: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate(APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate(PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate, APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth(By similarity).

Molecular Weight: 70 kDa

Gene ID: 9060

UniProt: O95340

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process