PAPSS2 antibody (AA 2-138)

Catalog No. ABIN7145552

This Rabbit Polyclonal antibody specifically detects PAPSS2 in ELISA and IF. It exhibits reactivity toward Human.

Quick Overview for PAPSS2 antibody (AA 2-138) (ABIN7145552)

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAPSS2 antibody is un-conjugated

Application: ELISA, Immunofluorescence (IF)

Product Details anti-PAPSS2 Antibody

Binding Specificity: AA 2-138

Purpose: PAPSS2 Antibody

Purification: Protein G purified

Purity: >95 %

Immunogen: Recombinant Human Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 protein (2-138AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for PAPSS2

Target: PAPSS2 (3'-phosphoadenosine 5'-phosphosulfate Synthase 2 (PAPSS2))

Alternative Name: PAPSS2

Background:

Background: Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate, APS appears to be only an intermediate in the sulfate-activation pathway. May have a important role in skeletogenesis during postnatal growth (By similarity).

Aliases: PAPSS2 antibody, ATPSK2Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2 antibody, PAPS synthase 2 antibody, PAPSS 2 antibody, Sulfurylase kinase 2 antibody, SK 2 antibody, SK2) [Includes: Sulfate adenylyltransferase antibody, EC 2.7.7.4 antibody, ATP-sulfurylase antibody, Sulfate adenylate transferase antibody, SAT), Adenylyl-sulfate kinase antibody, EC 2.7.1.25 antibody, 3'-phosphoadenosine-5'-phosphosulfate synthase antibody, APS kinase antibody, Adenosine-5'-phosphosulfate 3'-phosphotransferase antibody, Adenylylsulfate 3'-phosphotransferase)] antibody

UniProt: O95340

Pathways: Glycosaminoglycan Metabolic Process, Ribonucleoside Biosynthetic Process