XRN2 antibody

Catalog No. ABIN7111135

This Rabbit Polyclonal antibody specifically detects XRN2 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for XRN2 antibody (ABIN7111135)

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XRN2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-XRN2 Antibody

Purpose: XRN2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: 5'-3' exoribonuclease 2

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for XRN2

Target: XRN2 (5'-3' Exoribonuclease 2 (XRN2))

Alternative Name: XRN2

Background:

Synonyms: 5'-3' exoribonuclease 2|DHM1-like protein (DHP protein)|XRN2

Background: Possesses 5'->3' exoribonuclease activity(By similarity). May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains attached to the elongating polymerase. The processive degradation of this 3' fragment by this protein may promote termination of transcription. Binds to RNA polymerase II(RNAp II) transcription termination R-loops formed by G-rich pause sites(PubMed:21700224).

Molecular Weight: 108 kDa

Gene ID: 22803

UniProt: Q9H0D6