ADI1 antibody

Catalog No. ABIN7111195

This Rabbit Polyclonal antibody specifically detects ADI1 in WB, ELISA and IHC. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for ADI1 antibody (ABIN7111195)

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADI1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ADI1 Antibody

Purpose: ADI1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: acireductone dioxygenase 1

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ADI1

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Alternative Name: ADI1

Background:

Synonyms: Acireductone dioxygenase|Acireductone dioxygenase (Fe(2+)-requiring) (ARD', Fe-ARD)|Acireductone dioxygenase (Ni(2+)-requiring) (ARD, Ni-ARD)|Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1 (MTCBP-1)|Submergence-induced protein-like factor (Sip-L)|ADI1|MTCBP1

Background: Catalyzes the formation of formate and 2-keto-4-methylthiobutyrate(KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene(DHK-MTPene). Also down-regulates cell migration mediated by MMP14. Necessary for hepatitis C virus replication in an otherwise non-permissive cell line.

Molecular Weight: 20 kDa

Gene ID: 55256

UniProt: Q9BV57

Pathways: Methionine Biosynthetic Process