ADI1 antibody (AA 71-120)

Catalog No. ABIN7227224

The Rabbit Polyclonal anti-ADI1 antibody is suitable to detect ADI1 in samples from Human, Rat and Mouse. It has been validated for ELISA, IHC and IF.

Quick Overview for ADI1 antibody (AA 71-120) (ABIN7227224)

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ADI1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-ADI1 Antibody

Binding Specificity: AA 71-120

Purpose: Rabbit Anti-ADI1 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ADI1

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ADI1 protein at AA range: 71-120

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-200,ELISA 1:10000-20000,IF 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ADI1

Target: ADI1 (Acireductone Dioxygenase 1 (ADI1))

Alternative Name: ADI1

Background: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, Acireductone dioxygenase, Fe(2+-requiring, ARD, Fe-ARD, Membrane-type 1 matrix metalloproteinase cytoplasmic tail-binding protein 1, MTCBP-1, Submergence-induced protein-like factor, Sip-LADI1 encodes an enzyme that belongs to the aci-reductone dioxygenase family of metal-binding enzymes, which are involved in methionine salvage. This enzyme may regulate mRNA processing in the nucleus, and may carry out different functions depending on its localization. Related pseudogenes have been defined on chromosomes 8 and 20. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID: 55256

UniProt: Q9BV57

Pathways: Methionine Biosynthetic Process