ASCC3 antibody

Catalog No. ABIN7111240

This Rabbit Polyclonal antibody specifically detects ASCC3 in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ASCC3 antibody (ABIN7111240)

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-ASCC3 Antibody

Purpose: ASCC3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: activating signal cointegrator 1 complex subunit 3

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ASCC3

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Alternative Name: ASCC3

Background:

Synonyms: Activating signal cointegrator 1 complex subunit 3|ASC-1 complex subunit p200 (ASC1p200)|Helicase, ATP binding 1|Trip4 complex subunit p200|ASCC3|HELIC1|RQT2

Background: 3'-5' DNA helicase involved in repair of alkylated DNA. Promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3, enabling ALKBH3 to process alkylated N3-methylcytosine(3mC) within double-stranded regions. Enhances NF-kappa-B, SRF and AP1 transactivation.

Molecular Weight: 251 kDa

Gene ID: 10973

UniProt: Q8N3C0