ASCC3 antibody (AA 175-225)

Catalog No. ABIN7453037

Product Details anti-ASCC3 Antibody

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Binding Specificity: AA 175-225

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASCC3 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit anti-ASCC3 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 175 and 225

Isotype: IgG

Application Details

Application Notes:

IP: Not recommended

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for ASCC3

Target: ASCC3 (Activating Signal Cointegrator 1 Complex Subunit 3 (ASCC3))

Alternative Name: ASCC3 (ASCC3 Products)

Synonyms: ASC1p200 antibody, B630009I04Rik antibody, BC023451 antibody, D430001L07Rik antibody, D630041L21 antibody, Helic1 antibody, RNAH antibody, DJ467N11.1 antibody, HELIC1 antibody, dJ121G13.4 antibody, p200 antibody, activating signal cointegrator 1 complex subunit 3 antibody, Ascc3 antibody, ASCC3 antibody, ascc3 antibody

Background: Background: Activating signal cointegrator 1 complex subunit 3 (ASCC3) is a 3'-5' DNA helicase involved in repair of alkylated DNA. ASCC3 promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3, enabling ALKHB3 to process alkylated N3-methylcytosine (3mC) within double-stranded regions. ASCC3 also enhances NF-kappa-B, SRF and AP1 transactivation [taken from the Universal Protein Resource (UniProt) Q9Y3R0].

Gene ID: 10973

NCBI Accession: NP_006819

UniProt: Q8N3C0