AP3B1 antibody

Catalog No. ABIN7111311

The Rabbit Polyclonal anti-AP3B1 antibody (ABIN7111311) specifically detects AP3B1 in WB, ELISA, IP and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for AP3B1 antibody (ABIN7111311)

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-AP3B1 Antibody

Purpose: AP3B1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: adaptor-related protein complex 3, beta 1 subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000 IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AP3B1

Target: AP3B1 (Adaptor-Related Protein Complex 3, beta 1 Subunit (AP3B1))

Alternative Name: AP3B1

Background:

Synonyms: AP-3 complex subunit beta-1|Adaptor protein complex AP-3 subunit beta-1|Adaptor-related protein complex 3 subunit beta-1|Beta-3A-adaptin|Clathrin assembly protein complex 3 beta-1 large chain|AP3B1|ADTB3A

Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Molecular Weight: 140 kDa

Gene ID: 8546

UniProt: O00203

Pathways: SARS-CoV-2 Protein Interactome