AP3B2 antibody

Catalog No. ABIN7111312

This Rabbit Polyclonal antibody specifically detects AP3B2 in WB, ELISA and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for AP3B2 antibody (ABIN7111312)

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AP3B2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-AP3B2 Antibody

Purpose: AP3B2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: adaptor-related protein complex 3, beta 2 subunit

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000 IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for AP3B2

Target: AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))

Alternative Name: AP3B2

Background:

Synonyms: AP-3 complex subunit beta-2|Adaptor protein complex AP-3 subunit beta-2|Adaptor-related protein complex 3 subunit beta-2|Beta-3B-adaptin|Clathrin assembly protein complex 3 beta-2 large chain|Neuron-specific vesicle coat protein beta-NAP|AP3B2

Background: Subunit of non-clathrin-and clathrin-associated adaptor protein complex 3(AP-3) that plays a role in protein sorting in the late-Golgi/trans-Golgi network(TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. AP-3 appears to be involved in the sorting of a subset of transmembrane proteins targeted to lysosomes and lysosome-related organelles. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

Molecular Weight: 120-140 kDa

Gene ID: 8120

UniProt: Q13367