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AKR1C4 antibody

AKR1C4 Reactivity: Human, Mouse, Rat WB, ELISA, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7111464
  • Target See all AKR1C4 Antibodies
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Reactivity
    Human, Mouse, Rat
    Host
    • 28
    • 5
    • 1
    • 1
    Rabbit
    Clonality
    • 33
    • 2
    Polyclonal
    Conjugate
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AKR1C4 antibody is un-conjugated
    Application
    • 27
    • 18
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    aldo-keto reductase family 1, member C4(chlordecone reductase, 3-alpha hydroxysteroid dehydrogenase, type I, dihydrodiol dehydrogenase 4)
    Isotype
    IgG
    Top Product
    Discover our top product AKR1C4 Primary Antibody
  • Application Notes
    WB: 1:1000-1:10000, IF: 1:10-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
    Alternative Name
    AKR1C4 (AKR1C4 Products)
    Synonyms
    3-alpha-HSD antibody, C11 antibody, CDR antibody, CHDR antibody, DD-4 antibody, DD4 antibody, HAKRA antibody, aldo-keto reductase family 1 member C4 antibody, AKR1C4 antibody
    Background
    Synonyms:AKR1C4, HAKRA, CHDR, 3 alpha HSD1, Chlordecone reductase Background:Catalyzes the transformation of the potent androgen dihydrotestosterone(DHT) into the less active form, 5-alpha-androstan-3-alpha,17-beta-diol(3-alpha-diol). Also has some 20-alpha-hydroxysteroid dehydrogenase activity. The biotransformation of the pesticide chlordecone(kepone) to its corresponding alcohol leads to increased biliary excretion of the pesticide and concomitant reduction of its neurotoxicity since bile is the major excretory route.
    Molecular Weight
    37 kDa
    Gene ID
    1109
    UniProt
    P17516
    Pathways
    Steroid Hormone Biosynthesis
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