ALKBH3 antibody

Catalog No. ABIN7111481

The Rabbit Polyclonal anti-ALKBH3 antibody has been validated for WB, ELISA and IHC. It is suitable to detect ALKBH3 in samples from Human and Mouse.

Quick Overview for ALKBH3 antibody (ABIN7111481)

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-ALKBH3 Antibody

Purpose: ALKBH3 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: alkB, alkylation repair homolog 3(E. coli)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ALKBH3

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Alternative Name: ALKBH3

Background:

Synonyms: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3|Alkylated DNA repair protein alkB homolog 3 (hABH3)|DEPC-1|Prostate cancer antigen 1|ALKBH3|ABH3|DEPC1

Background: ALKBH3, also named as ABH3 and DEPC-1, is a dioxygenase that mediates demethylation of DNA and RNA containing 1-methyladenosine (m1A). It has a strong preference for single-stranded. ALKBH3 is requires molecular oxygen, alpha-ketoglutarate and iron. This gene has some isoforms with MW 19-25 kDa and 33 kDa.

Molecular Weight: 33 kDa

Gene ID: 221120

UniProt: Q96Q83

Pathways: DNA Damage Repair