ALKBH3 antibody (AA 110-190)

Catalog No. ABIN7227268

The Rabbit Polyclonal anti-ALKBH3 antibody (ABIN7227268) specifically detects ALKBH3 in ELISA and WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for ALKBH3 antibody (AA 110-190) (ABIN7227268)

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALKBH3 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ALKBH3 Antibody

Binding Specificity: AA 110-190

Purpose: Rabbit Anti-ALKB3 Polyclonal Antibody

Specificity: The antibody detects endogenous levels of ALKB3 protein

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human ALKB3 protein at AA range: 110-190

Isotype: IgG

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for ALKBH3

Target: ALKBH3 (AlkB, Alkylation Repair Homolog 3 (ALKBH3))

Alternative Name: ALKB3

Background: Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3, Alkylated DNA repair protein alkB homolog 3, hABH3, DEPC-1, Prostate cancer antigen 1The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E.coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. ALKBH3 (AlkB Homolog 3, Alpha-Ketoglutaratedependent Dioxygenase) is a Protein Coding gene. Diseases associated with ALKBH3 include Prostate Cancer. Among its related pathways are DNA Damage Reversal and DNA Double-Strand Break Repair.

Molecular Weight: 31kD

Gene ID: 221120

UniProt: Q96Q83

Pathways: DNA Damage Repair