APIP antibody

Catalog No. ABIN7111649

The Rabbit Polyclonal anti-APIP antibody is suitable to detect APIP in samples from Human, Mouse and Rat. It has been validated for WB and ELISA.

Quick Overview for APIP antibody (ABIN7111649)

Target: APIP (APAF1 Interacting Protein (APIP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APIP antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-APIP Antibody

Purpose: APIP antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: APAF1 interacting protein

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for APIP

Target: APIP (APAF1 Interacting Protein (APIP))

Alternative Name: APIP

Background:

Synonyms: Methylthioribulose-1-phosphate dehydratase (MTRu-1-P dehydratase)|APAF1-interacting protein (hAPIP)|APIP

Background: Catalyzes the dehydration of methylthioribulose-1-phosphate(MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate(DK-MTP-1-P). Functions in the methionine salvage pathway, which plays a key role in cancer, apoptosis, microbial proliferation and inflammation. May inhibit the CASP1-related inflammatory response(pyroptosis), the CASP9-dependent apoptotic pathway and the cytochrome c-dependent and APAF1-mediated cell death.

Molecular Weight: 27 kDa

Gene ID: 51074

UniProt: Q96GX9

Pathways: Methionine Biosynthetic Process