ASTL antibody

Catalog No. ABIN7111765

This Rabbit Polyclonal antibody specifically detects ASTL in ELISA and WB. It exhibits reactivity toward Human.

Quick Overview for ASTL antibody (ABIN7111765)

Target: ASTL (Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASTL antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Product Details anti-ASTL Antibody

Purpose: ASTL antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: astacin-like metallo-endopeptidase(M12 family)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ASTL

Target: ASTL (Astacin-Like Metallo-Endopeptidase (M12 Family) (ASTL))

Alternative Name: ASTL

Background:

Synonyms: Astacin-like metalloendopeptidase|Oocyte astacin|Ovastacin|ZP2-proteinase|ASTL

Background: Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding(By similarity).

Molecular Weight: 46 kDa

Gene ID: 431705

UniProt: Q6HA08