ABCC1 antibody

Catalog No. ABIN7111817

The Rabbit Polyclonal anti-ABCC1 antibody is suitable to detect ABCC1 in samples from Human, Mouse and Rat. It has been validated for WB, IHC and ELISA.

Quick Overview for ABCC1 antibody (ABIN7111817)

Target: ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ABCC1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-ABCC1 Antibody

Purpose: ABCC1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ABCC1

Isotype: IgG

Application Details

Application Notes: WB 1:500-1:1000, IHC 1:50-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for ABCC1

Target: ABCC1 (ATP-Binding Cassette, Sub-Family C (CFTR/MRP), Member 1 (ABCC1))

Alternative Name: ABCC1

Background:

Synonyms: Multidrug resistance-associated protein 1|ATP-binding cassette sub-family C member 1|Glutathione-S-conjugate-translocating ATPase ABCC1|Leukotriene C(4) transporter (LTC4 transporter)|ABCC1|MRP|MRP1

Background: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette(ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies(ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

Molecular Weight: 173 kDa

UniProt: P33527

Pathways: SARS-CoV-2 Protein Interactome