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BBS7 antibody

BBS7 Reactivity: Human, Mouse WB, ELISA, IHC, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7111938
  • Target See all BBS7 Antibodies
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Reactivity
    • 30
    • 2
    • 2
    Human, Mouse
    Host
    • 26
    • 3
    • 1
    Rabbit
    Clonality
    • 28
    • 2
    Polyclonal
    Conjugate
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This BBS7 antibody is un-conjugated
    Application
    • 25
    • 19
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    Bardet-Biedl syndrome 7
    Isotype
    IgG
    Top Product
    Discover our top product BBS7 Primary Antibody
  • Application Notes
    WB: 1:500-1:3000, IP: 1:500-1:1000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    BBS7 (Bardet-Biedl Syndrome 7 (BBS7))
    Alternative Name
    BBS7 (BBS7 Products)
    Synonyms
    BBS7 antibody, bbs2l1 antibody, BBS2L1 antibody, id:ibd5048 antibody, zgc:153772 antibody, 8430406N16Rik antibody, Bardet-Biedl syndrome 7 antibody, bardet-biedl syndrome 7 antibody, Bardet-Biedl syndrome 7 L homeolog antibody, Bardet-Biedl syndrome 7 (human) antibody, BBS7 antibody, bbs7 antibody, MICPUN_100192 antibody, MICPUCDRAFT_16331 antibody, bbs7.L antibody, Bbs7 antibody
    Background
    Synonyms:BBS2L1 Background:The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor(GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. The BBSome complex, together with the LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog(SHH) pathway regulation. Required for proper BBSome complex assembly and its ciliary localization.
    Molecular Weight
    80 kDa
    Gene ID
    55212
    UniProt
    Q8IWZ6
    Pathways
    Hedgehog Signaling
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