BCOR antibody

Catalog No. ABIN7111972

This Rabbit Polyclonal antibody specifically detects BCOR in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for BCOR antibody (ABIN7111972)

Target: BCOR (BCL6 Co-Repressor (BCOR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BCOR antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-BCOR Antibody

Purpose: BCOR antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: BCL6 co-repressor

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BCOR

Target: BCOR (BCL6 Co-Repressor (BCOR))

Alternative Name: BCOR

Background:

Synonyms: BCL-6 corepressor (BCoR)|BCOR|KIAA1575

Background: Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence-specific DNA-binding proteins such as BCL6 and MLLT3. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor. Involved in the repression of TFAP2A, impairs binding of BCL6 and KDM2B to TFAP2A promoter regions. Via repression of TFAP2A acts as a negative regulator of osteo-dentiogenic capacity in adult stem cells, the function implies inhibition of methylation on histone H3 'Lys-4'(H3K4me3) and 'Lys-36'(H3K36me2).

Molecular Weight: 186 kDa

Gene ID: 54880

UniProt: Q6W2J9