BMPR1A antibody

Catalog No. ABIN7112028

The Rabbit Polyclonal anti-BMPR1A antibody (ABIN7112028) specifically detects BMPR1A in WB, ELISA, IP and IF. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for BMPR1A antibody (ABIN7112028)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BMPR1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunofluorescence (IF)

Product Details anti-BMPR1A Antibody

Purpose: BMPR1A antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: bone morphogenetic protein receptor, type IA

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: BMPR1A

Background:

Synonyms: Bone morphogenetic protein receptor type-1A (BMP type-1A receptor, BMPR-1A)|Activin receptor-like kinase 3 (ALK-3)|Serine/threonine-protein kinase receptor R5 (SKR5)|BMPR1A|ACVRLK3|ALK3

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.

Molecular Weight: 60 kDa

Gene ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance