CAPZA1 antibody

Catalog No. ABIN7112263

This Rabbit Polyclonal antibody specifically detects CAPZA1 in WB, ELISA, IHC and IP. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CAPZA1 antibody (ABIN7112263)

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CAPZA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-CAPZA1 Antibody

Purpose: CAPZA1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: capping protein(actin filament) muscle Z-line, alpha 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:500-1:1000, IHC: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CAPZA1

Target: CAPZA1 (Capping Protein (Actin Filament) Muscle Z-Line, alpha 1 (CAPZA1))

Alternative Name: CAPZA1

Background:

Synonyms: F-actin-capping protein subunit alpha-1|CapZ alpha-1|CAPZA1

Background: F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments(barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins(such as gelsolin and severin), these proteins do not sever actin filaments.

Molecular Weight: 33 kDa

Gene ID: 829

UniProt: P52907

Pathways: Regulation of Actin Filament Polymerization