CHST15 antibody

Catalog No. ABIN7112281

This Rabbit Polyclonal antibody specifically detects CHST15 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for CHST15 antibody (ABIN7112281)

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHST15 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CHST15 Antibody

Purpose: CHST15 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: carbohydrate(N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CHST15

Target: CHST15 (Carbohydrate (N-Acetylgalactosamine 4-Sulfate 6-O) Sulfotransferase 15 (CHST15))

Alternative Name: CHST15

Background:

Synonyms: Carbohydrate sulfotransferase 15|B-cell RAG-associated gene protein (hBRAG)|N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase (GalNAc4S-6ST)|CHST15|BRAG|GALNAC4S6ST|KIAA0598

Background: Sulfotransferase that transfers sulfate from 3'-phosphoadenosine 5'-phosphosulfate(PAPS) to the C-6 hydroxyl group of the GalNAc 4-sulfate residue of chondroitin sulfate A and forms chondroitin sulfate E containing GlcA-GalNAc(4,6-SO(4)) repeating units. It also transfers sulfate to a unique non-reducing terminal sequence, GalNAc(4SO4)-GlcA(2SO4)-GalNAc(6SO4), to yield a highly sulfated structure similar to the structure found in thrombomodulin chondroitin sulfate. May also act as a B-cell receptor involved in BCR ligation-mediated early activation that mediate regulatory signals key to B-cell development and/or regulation of B-cell-specific RAG expression, however such results are unclear in vivo.

Molecular Weight: 49 kDa, 69 kDa

Gene ID: 51363

UniProt: Q7LFX5

Pathways: Glycosaminoglycan Metabolic Process