CES1 antibody

Catalog No. ABIN7112300

The Rabbit Polyclonal anti-CES1 antibody has been validated for WB, IHC and ELISA. It is suitable to detect CES1 in samples from Human and Mouse.

Quick Overview for CES1 antibody (ABIN7112300)

Target: CES1 (Carboxylesterase 1 (CES1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CES1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CES1 Antibody

Purpose: CES1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: carboxylesterase 1 (monocyte/macrophage serine esterase 1)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CES1

Target: CES1 (Carboxylesterase 1 (CES1))

Alternative Name: CES1

Background:

Synonyms: Liver carboxylesterase 1|Acyl-coenzyme A:cholesterol acyltransferase (ACAT)|Brain carboxylesterase hBr1|Carboxylesterase 1 (CE-1, hCE-1)|Cholesteryl ester hydrolase (CEH)|Cocaine carboxylesterase|Egasyn|HMSE|Methylumbelliferyl-acetate deacetylase 1|Monocyte/macrophage serine esterase|Retinyl ester hydrolase (REH)|Serine esterase 1|Triacylglycerol hydrolase (TGH)|CES1|CES2|SES1

Background: This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. This enzyme is the major liver enzyme and functions in liver drug clearance. Mutations of this gene cause carboxylesterase 1 deficiency. Three transcript variants encoding three different isoforms have been found for this gene.

Molecular Weight: 62 kDa

Gene ID: 1066

UniProt: P23141

Pathways: Monocarboxylic Acid Catabolic Process