CHMP1B antibody

Catalog No. ABIN7112644

This Rabbit Polyclonal antibody specifically detects CHMP1B in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHMP1B antibody (ABIN7112644)

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP1B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CHMP1B Antibody

Purpose: CHMP1B antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: chromatin modifying protein 1B

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Alternative Name: CHMP1B

Background:

Synonyms: Charged multivesicular body protein 1b|CHMP1.5|Chromatin-modifying protein 1b (CHMP1b)|Vacuolar protein sorting-associated protein 46-2 (Vps46-2, hVps46-2)|CHMP1B|C18orf2

Background: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

Molecular Weight: 30 kDa

Gene ID: 57132

UniProt: Q7LBR1