CHMP1B antibody (AA 101-199) (Biotin)

Catalog No. ABIN890538

The Biotin-conjugated Rabbit Polyclonal anti-CHMP1B antibody (ABIN890538) specifically detects CHMP1B in WB, ELISA, IHC (fro) and IHC (p). The antibody is reactive with Human samples.

Quick Overview for CHMP1B antibody (AA 101-199) (Biotin) (ABIN890538)

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHMP1B antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CHMP1B Antibody (Biotin)

Binding Specificity: AA 101-199

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHMP1B

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Alternative Name: CHMP1B

Background:

Synonyms: Charged multivesicular body protein 1b, CHM1B_HUMAN, CHMP1.5, CHMP1b, chmp1b, Chromatin-modying protein 1b, hVps46-2, Vacuolar protein sorting-associated protein 46-2, Vps46-2.

Background: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression

Gene ID: 57132