CXCR1 antibody

Catalog No. ABIN7112675

The Rabbit Polyclonal anti-CXCR1 antibody has been validated for WB, ELISA and IP. It is suitable to detect CXCR1 in samples from Human and Mouse.

Quick Overview for CXCR1 antibody (ABIN7112675)

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CXCR1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Product Details anti-CXCR1 Antibody

Purpose: CXCR1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: peptide, C-terminal

Immunogen: interleukin 8 receptor, alpha

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CXCR1

Target: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Alternative Name: CXCR1

Background:

Synonyms: C-X-C chemokine receptor type 1 (CXC-R1, CXCR-1)|CDw128a|High affinity interleukin-8 receptor A (IL-8R A)|IL-8 receptor type 1|CXCR1|CMKAR1|IL8RA

Background: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA(GRO) with a low affinity.

Molecular Weight: 50 kDa

Gene ID: 3577

UniProt: P25024

Pathways: cAMP Metabolic Process