CLCA2 antibody (AA 645-901)

Catalog No. ABIN7112700

This anti-CLCA2 antibody is a Rabbit Polyclonal antibody detecting CLCA2 in WB, ELISA and IHC. Suitable for Human and Mouse.

Quick Overview for CLCA2 antibody (AA 645-901) (ABIN7112700)

Target: CLCA2 (Chloride Channel Accessory 2 (CLCA2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CLCA2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CLCA2 Antibody

Binding Specificity: AA 645-901

Purpose: CLCA2 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 645-901aa

Immunogen: chloride channel accessory 2

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CLCA2

Target: CLCA2 (Chloride Channel Accessory 2 (CLCA2))

Alternative Name: CLCA2

Background:

Synonyms: Calcium-activated chloride channel regulator 2|Calcium-activated chloride channel family member 2 (hCLCA2)|Calcium-activated chloride channel protein 3 (CaCC-3, hCaCC-3)|Calcium-activated chloride channel regulator 2, 109 kDa form|Calcium-activated chloride channel regulator 2, 35 kDa form|CLCA2|CACC3

Background: Plays a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Involved in basal cell adhesion and/or stratification of squamous epithelia. May act as a tumor suppressor in breast and colorectal cancer. Plays a key role for cell adhesion in the beginning stages of lung metastasis via the binding to ITGB4.

Molecular Weight: 141 kDa, 35-40 kDa

Gene ID: 9635

UniProt: Q9UQC9