CHPF antibody

Catalog No. ABIN7112728

This Rabbit Polyclonal antibody specifically detects CHPF in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CHPF antibody (ABIN7112728)

Target: CHPF (Chondroitin Polymerizing Factor (CHPF))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHPF antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-CHPF Antibody

Purpose: CHPF N-Terminal antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: chondroitin polymerizing factor

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CHPF

Target: CHPF (Chondroitin Polymerizing Factor (CHPF))

Alternative Name: CHPF

Background:

Synonyms: Chondroitin sulfate synthase 2|Chondroitin glucuronyltransferase 2|Chondroitin-polymerizing factor (ChPF)|Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II|N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II|N-acetylgalactosaminyltransferase 2|CHPF|CSS2

Background: Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid(GlcUA) from UDP-GlcUA and N-acetylgalactosamine(GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PARK2 transport into the mitochondria. In collaboration with PARK2, isoform 2 may enhance cell viability and protect cells from oxidative stress.

Molecular Weight: 85 kDa

Gene ID: 79586

UniProt: Q8IZ52

Pathways: Glycosaminoglycan Metabolic Process, SARS-CoV-2 Protein Interactome