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CDYL antibody

This Rabbit Polyclonal antibody specifically detects CDYL in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.
Catalog No. ABIN7112758

Quick Overview for CDYL antibody (ABIN7112758)

Target

See all CDYL Antibodies
CDYL (Chromodomain Protein, Y-Like (CDYL))

Reactivity

  • 32
  • 11
  • 10
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human, Mouse, Rat

Host

  • 30
  • 1
  • 1
Rabbit

Clonality

  • 31
  • 1
Polyclonal

Conjugate

  • 16
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CDYL antibody is un-conjugated

Application

  • 21
  • 15
  • 4
  • 4
  • 2
  • 2
Western Blotting (WB), ELISA
  • Purification

    Immunogen affinity purified

    Purity

    ≥95 % as determined by SDS-PAGE

    Immunogen

    chromodomain protein, Y-like

    Isotype

    IgG
  • Application Notes

    WB: 1:500-1:2000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    -20 °C

    Storage Comment

    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

    Expiry Date

    12 months
  • Target

    CDYL (Chromodomain Protein, Y-Like (CDYL))

    Alternative Name

    CDYL

    Background

    Synonyms:CDYL1 Background:Acts as a RE1-silencing transcription factor(REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2(PRC2), acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

    Molecular Weight

    66 kDa, 60 kDa

    Gene ID

    9425

    UniProt

    Q9Y232
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