CDYL antibody
Quick Overview for CDYL antibody (ABIN7112758)
Target
See all CDYL AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Purification
- Immunogen affinity purified
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Purity
- ≥95 % as determined by SDS-PAGE
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Immunogen
- chromodomain protein, Y-like
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Isotype
- IgG
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Application Notes
- WB: 1:500-1:2000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- -20 °C
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Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
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Expiry Date
- 12 months
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- CDYL (Chromodomain Protein, Y-Like (CDYL))
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Alternative Name
- CDYL
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Background
- Synonyms:CDYL1 Background:Acts as a RE1-silencing transcription factor(REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2(PRC2), acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.
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Molecular Weight
- 66 kDa, 60 kDa
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Gene ID
- 9425
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UniProt
- Q9Y232
Target
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