CDYL antibody

Catalog No. ABIN7112758

This Rabbit Polyclonal antibody specifically detects CDYL in WB and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for CDYL antibody (ABIN7112758)

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDYL antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-CDYL Antibody

Purpose: CDYL antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: chromodomain protein, Y-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CDYL

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Alternative Name: CDYL

Background:

Synonyms: Chromodomain Y-like protein (CDY-like)|Crotonyl-CoA hydratase|CDYL|CDYL1

Background: Acts as a RE1-silencing transcription factor(REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2(PRC2), acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

Molecular Weight: 66 kDa, 60 kDa

Gene ID: 9425

UniProt: Q9Y232