CDYL antibody (AA 8-260) (Biotin)

Catalog No. ABIN7147711

Product Details anti-CDYL Antibody (Biotin)

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Binding Specificity: AA 8-260

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDYL antibody is conjugated to Biotin

Application: ELISA

Cross-Reactivity: Human

Purification: >95%, Protein G purified

Immunogen: Recombinant Human Chromodomain Y-like protein (8-260AA)

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CDYL

Target: CDYL (Chromodomain Protein, Y-Like (CDYL))

Alternative Name: CDYL (CDYL Products)

Synonyms: AI325931 antibody, CDYL1 antibody, chromodomain Y like antibody, chromodomain protein, Y chromosome-like antibody, chromodomain Y-like antibody, CDYL antibody, Cdyl antibody

Background:

Background: Acts as a RE1-silencing transcription factor (REST) corepressor that facilitates histone-lysine N-methyltransferase EHMT2 recruitment and H3K9 dimethylation at REST target genes for repression. Required for chromatin targeting and maximal enzymatic activity of polycomb repressive complex 2 (PRC2), acts as a positive regulator of PRC2 activity by bridging the pre-existing histone H3K27me3 and newly recruited PRC2 on neighboring nucleosomes. Has histone acetyltransferase activity, with a preference for histone H4.

Aliases: CDY-like antibody, CDY-like autosomal antibody, Cdyl antibody, CDYL: chromodomain protein Y-like antibody, CDYL1 antibody, CDYL1_HUMAN antibody, chromodomain protein Y chromosome-like 6 antibody, Chromodomain protein Y like antibody, Chromodomain Y-like protein antibody, DKFZP586C1622 antibody, MGC131936 antibody, OTTHUMP00000015984 antibody, OTTHUMP00000211185 antibody, OTTHUMP00000211186 antibody, OTTHUMP00000211189 antibody, testis-specific chromodomain Y-like protein antibody, Weakly similar to enoyl-CoA hydratase [H.sapiens] antibody

UniProt: Q9Y232