CIT antibody

Catalog No. ABIN7112858

The Rabbit Polyclonal anti-CIT antibody is suitable to detect CIT in samples from Human, Mouse and Rat. It has been validated for ELISA, WB and IF.

Quick Overview for CIT antibody (ABIN7112858)

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CIT antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-CIT Antibody

Purpose: CIT antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: Peptide

Immunogen: citron(rho-interacting, serine/threonine kinase 21)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CIT

Target: CIT (Citron (Rho-Interacting, serine/threonine Kinase 21) (CIT))

Alternative Name: CIT

Background:

Synonyms: Citron Rho-interacting kinase (CRIK)|Serine/threonine-protein kinase 21|CIT|CRIK|KIAA0949|STK21

Background: Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.

Molecular Weight: 230 kDa

Gene ID: 11113

UniProt: O14578

Pathways: SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection