COL6A1 antibody (AA 750-1028)

Catalog No. ABIN7112987

The Rabbit Polyclonal anti-COL6A1 antibody has been validated for WB, IHC, ELISA and IP. It is suitable to detect COL6A1 in samples from Human, Mouse and Rat.

Quick Overview for COL6A1 antibody (AA 750-1028) (ABIN7112987)

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL6A1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Product Details anti-COL6A1 Antibody

Binding Specificity: AA 750-1028

Purpose: COL6A1 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen:

Immunogen sequence: 750-1028aa

Immunogen: collagen, type VI, alpha 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:1000, IP: 1:500-1:1000, IHC: 1:50-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for COL6A1

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Alternative Name: COL6A1

Background:

Synonyms: Collagen alpha-1(VI) chain|COL6A1

Background: Type VI Collagen is a major structural component of microfibrils. Type VI Collagen was found to be present throughout the connective tissue and in the extracellular matrix of cultured fibroblasts(PMID: 6723253). It is a heterotrimer composed of three different chains: alpha-1(VI), alpha-2(VI), and alpha-3(VI) or alpha-5(VI) or alpha-6(VI). The alpha-1(VI) chain is encoded by COL6A1 gene. Mutations in this gene result in Bethlem myopathy and Ullrich congenital muscular dystrophy.

Molecular Weight: 140 kDa

Gene ID: 1291

UniProt: P12109

Pathways: Growth Factor Binding, SARS-CoV-2 Protein Interactome