COL6A1 antibody (AA 19-250)

Catalog No. ABIN6138847

Product Details anti-COL6A1 Antibody

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Binding Specificity: AA 19-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL6A1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: AQDEPETPRA VAFQDCPVDL FFVLDTSESV ALRLKPYGAL VDKVKSFTKR FIDNLRDRYY RCDRNLVWNA GALHYSDEVE IIQGLTRMPG GRDALKSSVD AVKYFGKGTY TDCAIKKGLE QLLVGGSHLK ENKYLIVVTD GHPLEGYKEP CGGLEDAVNE AKHLGVKVFS VAITPDHLEP RLSIIATDHT YRRNFTAADW GQSRDAEEAI SQTIDTIVDM IKNNVEQVCC SF

Cross-Reactivity: Human, Mouse

Characteristics: Polyclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 19-250 of human Collagen VI/Collagen VI/COL6A1 (NP_001839.2).

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Comment:

HIGH QUALITY

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for COL6A1

Target: COL6A1 (Collagen, Type VI, alpha 1 (COL6A1))

Alternative Name: COL6A1 (COL6A1 Products)

Synonyms: CBR antibody, SDR21C1 antibody, hCBR1 antibody, OPLL antibody, AI747156 antibody, Col6a-1 antibody, RGD1565398 antibody, COL6A1 antibody, carbonyl reductase 1 antibody, collagen type VI alpha 1 chain antibody, collagen, type VI, alpha 1 antibody, collagen, type VI, alpha 1 L homeolog antibody, collagen type VI alpha 3 chain antibody, collagen alpha-1(VI) chain antibody, CBR1 antibody, COL6A1 antibody, Col6a1 antibody, col6a1.L antibody, COL6A3 antibody, col6a1 antibody, LOC100623720 antibody

Background: The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.,COL6A1,BTHLM1,OPLL,UCHMD1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Collagen,COL6A1

Molecular Weight: 108 kDa

Gene ID: 1291

UniProt: P12109

Pathways: Growth Factor Binding, SARS-CoV-2 Protein Interactome