CPOX antibody

Catalog No. ABIN7113054

The Rabbit Polyclonal anti-CPOX antibody (ABIN7113054) specifically detects CPOX in WB, ELISA and IHC. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for CPOX antibody (ABIN7113054)

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CPOX antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-CPOX Antibody

Purpose: CPOX antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: coproporphyrinogen oxidase

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for CPOX

Target: CPOX (Coproporphyrinogen Oxidase (CPOX))

Alternative Name: CPOX

Background:

Synonyms: Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (COX, Coprogen oxidase, Coproporphyrinogenase)|CPOX|CPO|CPX

Background: The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

Molecular Weight: 36 kDa

Gene ID: 1371

UniProt: P36551