Exportin 2 antibody
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- Target See all Exportin 2 (CSE1L) Antibodies
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Exportin 2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- CSE1 chromosome segregation 1-like(yeast)
- Isotype
- IgG
- Top Product
- Discover our top product CSE1L Primary Antibody
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- Application Notes
- WB: 1:500-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- Exportin 2 (CSE1L) (CSE1 Chromosome Segregation 1-Like (CSE1L))
- Alternative Name
- CSE1L (CSE1L Products)
- Synonyms
- BcDNA:LD14270 antibody, CAS antibody, CG13281 antibody, Dcas antibody, Dmel\\CG13281 antibody, cas antibody, dcas antibody, l(2)k03902 antibody, CSE1L antibody, XPO2 antibody, Exportin-2 antibody, DKFZp459E1929 antibody, 2610100P18Rik antibody, AA407533 antibody, Capts antibody, Cas antibody, Xpo2 antibody, xpo2 antibody, CSE1 antibody, CAS/CSE1 segregation protein antibody, chromosome segregation 1 like antibody, exportin-2 antibody, chromosome segregation 1-like (S. cerevisiae) antibody, CSE1 chromosome segregation 1-like (yeast) antibody, CSE1 chromosome segregation 1-like L homeolog antibody, Cas antibody, CSE1L antibody, LOC100542094 antibody, cse1l antibody, Cse1l antibody, cse1l.L antibody
- Background
- Synonyms:CAS, XPO2 Background:Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates(cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex(NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP(induced by RANBP1 and RANGAP1, respectively) cause release of the importin-alpha from the export receptor. CSE1L/XPO2 then return to the nuclear compartment and mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP-and GDP-bound forms of Ran between the cytoplasm and nucleus.
- Molecular Weight
- 100-110 kDa
- Gene ID
- 1434
- UniProt
- P55060
- Pathways
- Protein targeting to Nucleus
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